The tenth edition is an important milestone in the life of a textbook. This occasion is a propitious time to look back on the origins of Basic Pathology， which are summed up best by quoting Stanley Robbins from the preface of the first edition （1971）：
”Of books as well as men， it may be observed that fat ones contain thin ones struggling to get out. In a sense， this book bears such a relationship to its more substantial progenitor， Robbins Pathology. It arose from an appreciation of the modem medical students dilemma. As the curriculum has become restructured to place greater emphasis on clinical experience， time for reading is correspondingly curtailed...In writing this book， rare and esoteric lesions are omitted without apology， and infrequent or trivial ones described only briefly. We felt it important， however， to consider rather fully the major disease entities.”
While the goals of ”baby Robbins” remain true to the vision of Stanley Robbins， this edition has been revised on the basis of a few additional principles.
目錄：
Introduction to Modern Pathology
CHAPTER 1 Cell Injury， Cell Death， and Adaptations
CHAPTER 2 Tissue Repair
CHAPTER 3 Hemodynamic Disorders
CHAPTER 4 Inflammation
CHAPTER 5 Diseases of the Immune System
CHAPTER 6 Neoplasia
CHAPTER 7 Genetic and Pediatric Diseases
CHAPTER 8 Environmental and Nutritional Diseases
CHAPTER 9 Cardiovascular System
CHAPTER 10 Lung
CHAPTER 11 Oral Cavities and Gastrointestinal Tract
CHAPTER 12 Liver and Gallbladder， Biliary Tract， and Pancreas
CHAPTER 13 Hematopoietic and Lymphoid Systems
CHAPTER 14 Kidney and Its Collecting System
CHAPTER 15 Male Genital System
CHAPTER 16 Female Genital System and Breast
CHAPTER 17 Endocrine System
CHAPTER 18 Bones， Joints， and Soft Tissue Tumors
CHAPTER 19 Peripheral Nerves and Muscles
CHAPTER 20 Central Nervous System
CHAPTER 21 Infectious Diseases
CHAPTER 22 Parasitosis
內容試閱：
Perface
The tenth edition is an important milestone in the life of a text book. This occasion is a propitious time to look back on the origins of Basic Pathology， which are summed up best by quoting Stanley Robbins from the preface of the first edition (1971):
“Of books as well as men， it may be observed that fat ones contain thin ones struggling to get out. In a sense， this book bears such a relationship to its more substantial progenitor， Robbins Pathology . It arose from an appreciation of the modern medical student ’ s dilemma. As the curriculum has become restructured to place greater emphasis on clinical experience， time for reading is correspondingly curtailed.…In writing this book， rare and esoteric lesions are omitted without apology， and infrequent or trivial ones described only briefly. We felt it important， however， to consider rather fully the major disease entities.”
While the goals of “baby Robbins” remain true to the vision of Stanley Robbins， this edition has been revised on the basis of a few additional principles.
? First， it is obvious that an understanding of disease mechanisms is based more than ever on a strong foundation of basic science. In keeping with this， we have always woven the relevant basic cell and molecular biology into the sections on pathophysiology in various chapters. In this edition we go one step further and introduce a new chapter titled “The Cellas a Unit of Health and Disease” at the very beginning of the book. In this chapter we have attempted to encapsulate aspects of cell and molecular biology that we believe are helpful in preparing readers for discussions of specific diseases. It is， in essence， a refresher course in cell biology.
? Second， as teachers， we are acutely aware that medical students feel overwhelmed by the rapid growth of infor mation about the molecular basis of disease. We have therefore excluded those new “breakthroughs” in the laboratory that have not yet reached the bedside. Thus， for example， the drugs developed for targeting cancer mutations that are still in clinical trials have not been discussed except in those rare instances in which the evidence of efficacy is close to hand. Similarly， in geneti cally heterogeneous disorders， we have focused on the most common mutations without providing a catalog of all the genes and polymorphisms involved. Thus， we have tried to balance discussions of advancement in sciences with the needs of students in the early stages of their careers. This effort required us to read each chapter as if it was written de novo and in many cases to remove parts of the text that had been present in the previous edition. It is our hope that these changes will unburden the students and that the tenth edition will be seen as an up to date yet simple to comprehend book.
? Third， because illustrations facilitate the understanding of difficult concepts such as control of the cell cycle and the actions of cancer genes， the art has been significantly revised and enhanced by adding depth so that the fourcolor figures are seen in threedimensions.
? Finally， we have added a board of clinical consultants to help us in keeping the clinical content accurate and up to date.
As an additional “tool” to help students focus on the fundamentals， we have continued the use of Summary boxes designed to provide key “take home” messages. These have been retained at the risk of adding a few addi tional pages to the book because students have uniformly told us that they find them useful.
Although we have entered the genomic era， the time honored tools of gross and microscopic analysis remain useful， and morphologic changes are highlighted for ready reference. The strong emphasis on clinicopathologic correlations is maintained， and， wherever understood， the impact of molecular pathology on the practice of medicine is emphasized. We are pleased that all of this was accomplished without a significant “bulge” in thewaistline of the text.
We continue to firmly believe that clarity of writing and proper use of language enhance comprehension and facilitate the learning process. Those familiar with the previous editions will notice significant reorganization of the text in many chapters to improve the flow of information and make it more logical. We are now in the digital age， so the text will be available online. In addition， over 100 updated and revised cases developed by one of us (VK) will also be available， linked to the electronic version of the text. We hope that these interactive cases will enhance and reinforce learning of pathology through application to clinical cases.
It is a privilege for us to edit this book， and we realize the considerable trust placed in us by students and teachers of pathology. We remain acutely conscious of this responsibility and hope that this edition will be worthy of and possibly enhance the tradition of its forebears.
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